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KMID : 0860920040060010016
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2004 Volume.6 No. 1 p.16 ~ p.22
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Chronic Inflammatory Demyelinating Poly neuropathy: Comparison of Clinical and Electrophsiological Features in Patients with and without Diabetes
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Kwon Seok-Beom
Kwon Ki-Han
Jung San
Cho Soo-Jin
Minn Yang-Ki
Choi Hui-Chul
Hwang Sung-Hee
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Abstract
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Objectives: There is growing evidence that idiopathic chronic inflammatory demyelinating polyneuropathy
(I-CIDP) and polyneuropathy in patients with diabetes mellitus (DM) that meets the clinical and
electrophysiological criteria for CIDP (DM-CIDP) have many similarities. We performed this study to
determine whether a subset of DM-CIDP are similar to I-CIDP employing proposed clinical and electrophysiologic
criteria for CIDP.
Methods: We compared the clinical (age, sex, symptom duration, pattern, course, motor scale, sensory
scale, total clinical scale, and M-Rankin score, etc.) and electrodiagnostic (routine nerve conduction studies
including median, ulnar, peroneal, and posterior tibial nerves) features of 9 patients (M=5, F=4) with
DM-CIDP to those of 11 patients (M=4, F=7) with I-CIDP.
Results: The patients with DM-CIDP displayed clinical, electrophysiologic features that were similar to
those in patients with I-CIDP.
Conclusion: Our study showed the influences of diabetes in patients with CIDP are insignificant and
DM-CIDP is electrophysiologically indistinguishable from idiopathic CIDP. It is important to separate
immune-mediated, demyelinating polyneuropathy in diabetic patients (DM-CIDP) from axonal polyneuropathy
because the former responds to immunomodulatory treatment.
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KEYWORD
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Short segment nerve conduction study, sensitivity
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